eGFR is calculated using serum creatinine levels, age, sex, and sometimes race.

It reflects the rate at which blood is filtered through the glomeruli in the kidneys.

Clinical uses include:

Detecting early kidney damage.

Staging chronic kidney disease (CKD).

Monitoring progression of kidney disease.

Guiding medication dosing adjustments in renal impairment.

Often performed alongside serum creatinine, BUN, and urinalysis for comprehensive renal evaluation.

Analyte: Estimated Glomerular Filtration Rate (eGFR).

Normal Range (varies by lab):

≥ 90 mL/min/1.73 m² → Normal kidney function.

60–89 mL/min/1.73 m² → Mildly decreased function.

30–59 mL/min/1.73 m² → Moderate decrease (CKD stage 3).

15–29 mL/min/1.73 m² → Severe decrease (CKD stage 4).

< 15 mL/min/1.73 m² → Kidney failure (CKD stage 5).

Abnormal Findings:

Low eGFR: Indicates reduced kidney function.

Trend monitoring: Persistent decline suggests progressive CKD.

Clinical Use:

Provides a direct measure of kidney function.

Helps guide diagnosis, staging, and treatment planning.

Supports nephrology, internal medicine, endocrinology, and general practice evaluations.